What is PDT photodynamic therapy acne treatment?
Photodynamic therapy (PDT), sometimes called photochemotherapy, is a light therapy involving light and photosensitizers. PDT has been proven to kill microbial cells, including bacteria, fungi and viruses. PDT skin is widely used to treat acne problems. This treatment is especially useful in cases of severe acne that do not respond to other treatments. PDT acne treatment also has effects on other skin conditions such as sunburned skin, precancerous cells and skin infections. PDT Photodynamic Therapy also reduces the size and activity of oil-producing glands on the skin, called the sebaceous glands. Excessive activity and inflammation of these glands can cause more severe acne. PDT photodynamic therapy is often more effective for inflammatory acne than non-inflammatory acne.
New concept PDT GEL riboflavin and tryptophan treatment principle
Photosensitizer is very important in PDT photodynamic therapy
1. Riboflavin activates tryptophan after exposure to blue light to form active free radicals.
2. Active radicals react with water molecules to produce ROS
3. ROS has the effect of reducing the secretion of acne bacteria and sebum
4. After the influence of tryptophan, by-products rapidly decompose as amino acids are discharged through metabolic pathways in the skin.
5. It does not cause any side effects, no need to worry about redness, burning or tanning
Why not use chlorophyll ALA aminolevulinic acid component of photosensitizer?
5-Aminolevulinic acid (ALA), an endogenous biochemical substance produced by ALA dehydratase and a series of enzymatic actions to produce protoporphyrin IX (PPIX) with strong photosensitivity. The synthesis speed of PPIX depends on the picking speed of this product, and this product is regulated by the feedback of free hemoglobin concentration. The exogenous product can bypass the feedback inhibition system and make the cells synthesize a sufficient amount of PPIX. The acne containing PPIX is irradiated with 420-640 nm light, and singlet oxygen (-O2) is generated during energy transfer. When the oxygen reaches a certain concentration, cell death (phototoxicity) can be induced.
Side effects: When treated with ALA, there is no selective destruction of normal tissues around it, such as oxidized proteins, liposomes and other subcutaneous cell structures. Oxygen free radicals generated under the pathological conditions of this product overload will lead to Acute periodic porphyria. In addition, this product will cause the release of iron ions in ferritin. Which will aggravate the oxidation of cells, it will lead to acute periodic porphyria. Some people will have erythema and swelling. ALA aminolevulinic acid also causes pigmentation, which is an anti-black phenomenon in some people during the treatment.
PDT acne treatment application process
1. Clean and disinfect skin before doing PDT photodynamic therapy
2. Squeeze the acne on your face (use a needle to gently puncture the area of the acne and squeeze out the pus)
3. Remove the cover of PDT Gel and replace it with a closed conical cover
4. Apply PDT Gel to your face, avoiding applying near the lips and around your eyes
5. Cover the face with plastic wrap, leave the lips and eyes area
6. Put the towel on your face for 20 minutes to block the light source to allow the product to fully penetrate. If you operate in a lighted room, you need to turn off the light.
7. Turn on the 415nm, 635nm pulsed LED light, each pulse for 10 minutes
8. Complete treatment, clean the skin
9. Place the Glamour Bio Cellulose Repair Mask for 20 minutes to clam your skin.
10. Always apply sunscreen after treatment, you need to apply sunscreen during the whole treatment period.
PDT photodynamic acne therapy usually takes 3 to 5 sessions for a complete treatment, depending on the skin condition of each patient. Each treatment interval is one week, but can be adjusted according to the patient’s skin condition. You can perform other skin treatment when doing PDT photodynamic therapy.
1. You can wash your face or having light makeup on the same day after treatment.
2. Please be gently cleaning your face to avoid irritating the skin.
3. Please try to avoid UV rays during the whole PDT photodynamic acne treatment always remember to apply sunscreen.
4. Please do not go to sauna, or having heavry exercise, etc. for 2-3 days after use.