Allergan Innotox,The first liquid botullinum toxin botox developed by Medytox
Innotox is predicted by the same Hall strain of C.botulinum as Neuronox and Botox. The molecular weight of Innotox analyzed using size exclusion SE-HPLC is approximately 900 kDa. Which is highly comparable to those of Neuronox and Botox.
Innotox is the world’s first liquid injectable form of Botulinum Toxin Type A, approved by KFDA in South Korea, 2013. Innotox is provided as a ready to use sterile liquid with 4U/0.1ml concentration. Therefore, no risk of contamination or inaccurate dosing due to human errors during reconstitution exists. Innotox ultimately enhances the treatment safety and efficacy. Professionals no longer needs to mix botox with saline anymore by using Innotox. Furthermore, its storage and reuse are more convenient, and Innotox has a long stability with an expiration of 36 months under 2 to 8 degree storage conditions. Shipping and delivery for Innotox is much more easier compares to bolutax or any other lyophilized white powder Botulinum Toxin. You should always buy Innotox online from trusted suppliers.
Differences between Innotox and other brand of Botulinum Toxin
Another key characteristic of Innotox is that it excludes the use of substances of animal origin in the manufacturing process. This process eliminates the risks associated with animal-based proteins. Moreover, it excludes human serum albumin as an excipient of the final product to avoid any risk associated with diseases of human blood origin. Instead it contains methionine and polysorbate as a stabilizer.
The safety and efficacy of Innotox and Botox were compared at a 1:1 dose ratio for treating glabellar lines in a double-blinded, randomized, phase III multi center study with 168 subjects. The patients, aged 20 to 65 years with moderate-to-severe glabellar lines. They were randomly treated with 20U of Innotox or Botox and subsequently assessed by blinded investigators. The improvement rate at both maximum frown and rest was not significantly different between the Innotox and Botox groups. No severe adverse drug reactions were observed.
Innotox is “bio-better” than Botox for several reasons such as from a plant-origin culture rather than the animal-origin culture. The most important of which is that Innotox is longer-lasting. As a beauty treatment, one of Botox’s advantages is low cost, an average of under $400 per treatment compare to a $30000 cost of face lift surgery. However, Botox treatments must be inject every four to six months to maintain the best result. Innotox is appealing to patients since it could last some 20% longer compare to botox, which reduces the number of doctor visits and procedures that are necessary for the same effect.
With these advantages, Allergan, the Botox manufacturer, made an exclusive license agreement to market Innotox worldwide, excluding Korea and Japan. It is available in vials of 25U and 50U. Allergan has been impressed with this technology , even though still in the approval stages, that Allergan has contracted to license Medytox’s next-generation neurotoxin technology for a substantial fee of $365 million. The “out-licensed” technology includes new manufacturing processes, such as starting from a plant-origin culture rather than the animal-origin culture used for Innotox.